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. Author manuscript; available in PMC: 2014 Dec 12.
Published in final edited form as: J Med Chem. 2013 Nov 21;56(23):9471–9481. doi: 10.1021/jm400794z

Table 1.

ΔTm value of (CUG)12 upon adding ligand in a 1:1 ratio.a

Ligand Solution ΔTm(°C)
2 5% DMSO 1.8 ± 0.61
7 5% DMSO 2.7 ± 0.4
4 N.S. ______
12 5% DMSO N.D.
13 5% DMSO N.D.
5 N.S. ______
8 5% DMSO 1.8 ± 0.2
6 N.S. ______
9 Aqueous 9.3 ± 0.6
10 Aqueous 9.6 ± 1.3
11 Aqueous 8.4 ± 2.1
a

Each value is mean ± s.d. of three independent experiments.

N.S. – not sufficiently soluble.