Table 2.

Antitrypanosomal activity of selected compounds in the T. b. rhodesiense acute mouse model at doses of 4×50 mg/kg^a.

Compd	Curesb	Mean Survival Daysc
Control	------	6–10
1	2/4	39
2	4/4	>60
5	4/4	>60
6	4/4	>60
7	4/4	>60
8	0/4	11
10	2/4	34
12	0/4	toxicd

^aAdministered ip on days 3–6 post-infection.

^bCure is defined as survival for more than 60 days after infection without a parasitemia relapse.

^cMean survival days is determined for mice with and without parasitemia relapse.

^dMice died following first compound dose.