Anomeric (a) and “ring” (b) regions of the 1H/13C HSQC NMR spectra of RO-tinzaparin (red spots) superimposed on the spectrum of the corresponding unmodified LMWH (blue spots) Symbols for typical end-group signals are framed with rectangles
A – glucosamine, A* – N-sulfate-glucosamine-3-O-sulfate, ΔU2S – 4,5-unsaturated 2-O-sulfated uronic acid, I/G – iduronic and glucuronic acids, GLR – glucuronic acid of the linkage region sequence, gsI/gsG – glycol-split iduronic and glucuronic acids, gsU – glycol-split uronic acids, Gal – galactose, Xyl – xylose, Ser - serine