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Distribution of recurrent disease by extracapsular extension grade
| Grade | n | Recurrence? (%) | Site |
|---|---|---|---|
| 0 | 13 | 1 (8) | Distant metastasis |
| 1 | 25 | 0 (0) | n/a |
| 2 | 7 | 1 (14) | Local |
| 3 | 19 | 1 (5) | Distant metastasis |
| 4 | 37 | 7 (19)a,b | 1 regional |
| 2 regional+distant metastasis | |||
| 4 distant metastasis |
Six of seven were p16 positive (all 4+).
Recurrence for extracapsular extension grade 4 was higher: P = 0.04.
