Table 3.
Clinicopathologic and Recurrence Score results in patients with a treatment change ( n = 24)
| Type of treatment change | ||
|---|---|---|
| Pre-testing: HT. Post-testing: CHT. | Pre-testing: CHT. Post-testing: HT. | |
| (n = 11) | (n = 13) | |
| Age a | ||
| Mean (SD), years | 54.2 (3.4) | 55.1 (9.5) |
| Median (range), years | 54 (46-58) | 56 (35-72) |
| Tumor size b | ||
| Mean (SD), mm | 15.6 (5.7) | 20.4 (7.6) |
| Median (range), mm | 14 (10-28) | 20.5 (10-32) |
| Nodal status, c n (%) | ||
| Node negative | 10 (100) | 8 (72.7) |
| Node positive | 0 (0) | 3 (27.3) |
| Tumor grade, d n (%) | ||
| 1 | 1 (9.1) | 0 (0) |
| 2 | 8 (72.7) | 7 (63.6) |
| 3 | 2 (18.2) | 4 (36.4) |
| Type of surgery, e n (%) | ||
| Lumpectomy | 10 (90.9) | 9 (69.2) |
| Mastectomy | 1 (9.1) | 4 (30.8) |
| Recurrence Score result f | ||
| Mean (SD) | 27.3 (1.7) | 21.1 (3.0) |
| Median (range) | 28 (23-29) | 20 (18-28) |
CHT chemohormonal therapy; HT hormonal therapy; SD standard deviation.
a P = 0.76 (t-test for comparing means).
b P = 0.11 (t-test for comparing means). Tumor size information was unavailable for 1 patient in the chemohormonal to hormonal therapy group.
c P = 0.21 (Fisher’s exact test). Nodal status information was unavailable for 1 patient in the hormonal therapy to chemohormonal therapy group and 2 patients in the chemohormonal to hormonal therapy group.
d P = 0.64 (Fisher’s exact test). Grade information was unavailable for 2 patients in the chemohormonal to hormonal therapy group.
e P = 0.33 (Fisher’s exact test).
f P = 0.0014 (MWW test).