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Cell cycle modulators and their molecular target optimal therapeutic inhibitors.
| Agent | Target |
|---|---|
| Staurosporine | CDK1, CDK2, CDK4 |
| Flavopiridol | CDK1, CDK2, CDK4, CCND |
| Butyrolactone | CDK1, CDK2 |
| Paullones | CDK1, CDK2, CDK5 |
| Indirubin | CDK1, CDK2, CDK4, CDK5 |
| Rapamycin | CCND, CCNA |
| Olomoucine | CDK1, CDK2, CDK5 |
| Isopentenyladenine | CDK1, CDK2 |
