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Figure 4. Effects of BBMD3 on cell growth and regulatory proteins of cell cycle progression in osteosarcoma cells. (A and B) Rates of KHOS and G292 cell growth were determined by counting live cells after 24 h BBMD3 treatment with Trypan blue staining. (C) Effects of BBMD3 on cyclin D1, D2 and E, positive regulators for cell cycle, and p21Cip1 and p27Kip1, negative regulator for cell cycle in KHOS, G292, and MG-63 cells after 24 h BBMD3 treatment.
