Figure 2. Inflammatory markers and acute phase reactants in sera of infected cynomolgus macaques. Serum was isolated from NHP blood prior to infection (Day −3, baseline) and 2, 5, 9, 11, and 13 d following IAV inoculation. NHPs receiving S. aureus (USA300 and USA300Δpvl) were inoculated on day 5. Sera from individual animals were analyzed for C-reactive protein, IL-1ra, haptoglobin, and myeloperoxidase as described in the Methods.