Table 1.
Areas of significant phenotypic correlation with cerebellar activation.b
| Phenotype | Positive correlation with activation |
Negative correlation with activation |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cluster size in voxels | Peak MNIa coordinates |
Lobule(s) | Mean r (range) | Cluster size in voxels | Peak MNI coordinates |
Lobule(s) | Mean r (range) | |||||
| x | y | z | x | y | z | |||||||
| Age | 173 | 58 | –66 | –33 | R VIIa Crus I | 0.12 (0.10, 0.21) | 584 | –38 | –62 | –47 | L VIIb; L VIIa Crus II; L VIIa Crus I; L VIIIa | –0.14 (–0.10, –0.27) |
| Sex (males relative to females) | 633 | –44 | –60 | –47 | L VIIa Crus II; L VIIIa; L X; L VIIb | 0.14 (0.10, 0.24) | 3428 | –56 | –60 | –37 | L VIIa Crus I; R VIIa Crus I; R IX; L VI; Vermis R IX; Vermis R VIIIb | –0.15 (–0.10, –0.28) |
| 522 | –24 | –82 | –25 | L VIIa Crus I; L VI | ||||||||
| 147 | 42 | –44 | –31 | R VI; R V; R I-IV | ||||||||
| 116 | –8 | –76 | –41 | L VIIIa; R VIIIa; R VIIb; L VIIa Crus II; Vermis R VIIIb; Vermis L VIIIa | ||||||||
| 0-Back accuracy | 481 | –38 | –72 | –25 | L VIIa Crus I; L VI | 0.12 (0.10, 0.18) | - | - | - | - | - | - |
| 210 | –4 | –48 | –7 | L I-IV; R I-IV | - | - | ||||||
| 0-Back response time | 222 | 34 | –60 | –39 | R VIIa Crus I/II; R VIIIa; Vermis R VIIIa; Vermis L VIIIa; Vermis L VIIb | 0.12 (0.10, 0.17) | - | - | - | - | - | - |
| 196 | –10 | –62 | –31 | L IX; L VIIIb | ||||||||
| 2-Back accuracy | 575 | –32 | –66 | –47 | L VIIb; L VIIIb; L VIIIa; LX | 0.14 (0.10, 0.23) | 1306 | 30 | –66 | –35 | R VIIa Crus I; R VIIIa; R VI; L I-IV | –0.14 (–0.10, –0.26) |
| 316 | –2 | –58 | –27 | Vermis L IX; Vermis R IX; L V | 536 | –4 | –82 | –29 | Vermis L VIIb; Vermis L VIIa Crus II; R VIIa Crus II; L VI; R VIIa Crus I; L VIIa Crus II | |||
| 294 | –56 | –70 | –35 | R VIIa Crus I; R VIIa Crus II; L VIIa Crus I | ||||||||
| 2-Back response time | 1840 | 34 | –64 | –29 | R VIIa Crus I; Vermis L VI; Vermis L VIIb; Vermis L VIIIa | 0.14 (0.10, 0.24) | - | - | - | - | - | - |
| Full-scale IQ | 1478 | –30 | –60 | –23 | L VI; Vermis R IX | 0.14 (0.10, 0.25) | 578 | 42 | –62 | –43 | R VIIa Crus II; R VIIa Crus I | –0.14 (–0.10, –0.23) |
| 680 | –18 | –44 | –43 | L X; L IX; L VIIIb; L VIIIa; L VIIa Crus II | 408 | –58 | –62 | –41 | L VIIa Crus I; L VIIa Crus II | |||
| Cerebellar gray matter volume | 799 | –18 | –50 | –47 | L VIIIb; L VIIIa; L IX; L VIIb | 0.13 (0.10, 0.21) | 948 | 44 | –66 | –29 | R VIIa Crus I; R VI | –0.13 (–0.10, –0.26) |
| 325 | –42 | –58 | –41 | L VIIa Crus I; L VIIa Crus II | ||||||||
| 282 | –22 | –30 | –29 | L I-IV and V | ||||||||
a
Abbreviations: L, left hemisphere; MNI, Montréal Neurological Institute; R, right hemisphere.
b
The phenotypic correlations between n-back task strategy (spatial relative to numerical) and activation did not survive cluster thresholding.