Skip to main content
. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: J Immunol. 2014 Jan 17;192(4):1587–1596. doi: 10.4049/jimmunol.1301893

Figure 3. IgG2c anti-FliC responses are partially TLR5- and inflammasome-dependent.

Figure 3

TLR5−/− (n=19) (A, D), Naip5−/− (n=9) (B, E), and Casp1−/− (n=14) (C, F) mice were immunized twice on day 1 and day 21 and sera collected on days 14 and 35. Naïve, day 14, and day 35 sera were analyzed for IgG1 (A–C) and IgG2c (D–F) isotype specific antibody responses against FliC by ELISA. Data is a combination of 2–3-independent experiments with n = 3–6 per experiment. Statistical analyses were done using Mann-Whitney analysis of individual groups: *= P < 0.05, ** = P < 0.01.