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. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: J Immunol. 2014 Jan 17;192(4):1587–1596. doi: 10.4049/jimmunol.1301893

Figure 5. IgA anti-FliC responses are TR5- & MyD88-dependent.

Figure 5

C57BL/6 (n=17) (A), TLR5−/− (n=14) (B), Naip5−/− (n=9) (C), and Casp1−/− (n=11) (D), TLR5−/−/Casp1−/−, DKO (n=9) (E), MyD88−/− (n=11) (F) mice were immunized on day 1 and day 21 and sera was collected on days 0 (naïve), 14 and 35. Naïve and day 35 sera (boost) were analyzed for IgA specific antibody responses against FliC by ELISA. Data is a combination of 2–3-independent experiments with n = 3–6 per experiment. Statistical analyses were done using Mann-Whitney analysis of individual groups: *= P < 0.05, *** = P < 0.001.