Table 2. Toxicities.
Grade 3 or higher non-hematologic toxicities regardless of attribution*
| TOXICITY | GRADE | # EVENTS |
|---|---|---|
| Metabolic | ||
| Hyperglycemia | 3 | 2 |
| Acidosis | 4 | 1 |
| Low albumin | 3 | 4 |
| Tumor lysis | Present | 1 |
| Pulmonary | ||
| ARDS | 4 | 2 |
| Bronchospasm | 3 | 1 |
| Infiltrates | 3/4 | 2/1 |
| Dyspnea | 3/4 | 3/2 |
| Other resp complaint | 3 | 1 |
| Cardiac | ||
| Increased troponin I | 3 | 1 |
| Atrial fibrillation | 4 | 1 |
| Ventricular arrhythmia | 5 | 1 |
| Hypotension | 4 | 1 |
| Neurologic | ||
| Peripheral neuropathy (sensory) | 3 | 2 |
| Limb pain NOS | 3 | 1 |
| Renal | ||
| Insufficiency | 3 | 1 |
| Constitutional | ||
| Fatigue | 3 | 5 |
| Other | ||
| Increased AST/ALT | 3 | 2 |
| Hemorrhage | 3 | 5 |
| Thrombosis | 3 | 2 |
| Increased INR | 3 | 1 |
*
Clinically insignificant and correctable electrolyte abnormalities are not included in this list.