Table 4.
Distribution of scoring points among 302* HIV-positive patients with TB, and performance for identification of patients with <100 CD4 cells/mm3
| Score | CD4 < 100 (n) | CD4 100–350 (n) | CD4 > 350 (n) | Sensitivity (%) | Specificity (%) | Positive predictive value (PPV) (%) | Negative predictive value (NPV) (%) |
|---|---|---|---|---|---|---|---|
| 0 | 1 | 10 | 9 | 100 | 8 | 25 | 95 |
| 1 | 3 | 17 | 18 | 99 | 24 | 27 | 93 |
| 2 | 11 | 31 | 15 | 95 | 44 | 30 | 87 |
| 3 | 10 | 26 | 11 | 81 | 61 | 33 | 85 |
| 4 | 5 | 17 | 4 | 68 | 70 | 37 | 84 |
| 5 | 3 | 12 | 5 | 61 | 78 | 41 | 84 |
| 6 | 11 | 15 | 6 | 57 | 87 | 47 | 82 |
| 7 | 15 | 10 | 4 | 43 | 93 | 53 | 78 |
| >7 | 18 | 14 | 1 | 23 | 100 | 55 | 75 |
| Total | 77 | 152 | 73 |
CD4 cell values in cells/mm3.
Score cutoff rounded up to nearest integer. Sensitivity and PPV of being at threshold or above. Specificity and negative predictive value of being at threshold or below.
*
Only patients with no missing values were included in this analysis.