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. 2014 Feb 14;20(6):1614–1622. doi: 10.3748/wjg.v20.i6.1614

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Histopathological examination of stomach sections. A: Hematoxylin-eosin stained results showed severe degenerative changes in glandular region, epithelial folds and connective septa in aspirin-induced mucosal tissue (1, × 100 and 2, × 200), while hydrogen-rich water (HRW) pretreatment displayed slight changes (3, × 100 and 4, × 200); B: The gastric mucosal damage score in four groups. The mean scores are significantly higher in the aspirin group and HRW plus aspirin group (HRW + Asp) when compared with the normal control group and HRW alone group (^bP < 0.01). Pretreatment with HRW could significantly decrease the damage score in HRW + aspirin group (Asp) group when compared with aspirin group (^aP < 0.05).