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. 2014 Jan 15;4(1):6–13.

Figure 5.

Figure 5

Reversible suppression of cardiomyocyte metabolic activity following pulse treatment of cardiomyocytes with Lac alone is more sustained when followed by α1-MAO. RNVCs were pulse-treated with Lac, 5 µmol/l, for 30 min and then maintained in culture for up to 24 h. In a separate set of experiments, RNVCs were pulse-treated with Lac, 5 µmol/l, for 30 min after which the cells were incubated with α1-MAO for 16 and 24 h. Cells were assessed for (A) metabolic activity and (B) BrdU uptake at the indicated times. The values represent the means ± SEM of 3 to 8 separate experiments. *P<0.05 (ANOVA) when compared with 0.5 h time point. ‡P<0.05 (t-test) when compared with corresponding Lac alone group only.