Tim-1-Fc protects Bm12-derived cardiac grafts from rejection in T-bet deficient recipients. A: Survival rate of Bm12-derived cardiac grafts in T-bet-/- recipients after treating with Tim-1-Fc or control IgG (n=5 for each study group). B: Results for H&E staining and vasculopathy scores of cardiac grafts after day 14 of transplantation. C: Relative expression levels for IL-2, IL-4, IFN-γ, IL-17, CD11b and CD3 in the grafts after 14 days of transplantation. D: Serum levels for cytokines IL4, IFN-γ and IL-17 in the recipient mice. All data are presented as means ± SD, and 3 replications were included for each assay.