Table 3.

Univariate and Multivariate analyses of the overall survival of the 246 gastric cancer patients

Variables	Univariate analysis		Multivariate analysis
	No.	P valuea	Hazard Ratio	95% CI	P valuea
Per1		< 0.001	1.245	0.887-1.747	0.205
Low expression	143
High expression	103
Per2		0.002	1.462	1.053-2.031	0.023
Low expression	160
High expression	86
Gender		0.177
Female	65
Male	181
Size (cm)		0.001	1.318	0.971-1.789	0.076
≤ 5.0	154
> 5.0	92
Age (years)		0.598
≤ 60	131
> 60	115
Depth of invasion		< 0.001	2.581	1.219-5.464	0.013
T1 + T2	48
T3 + T4	198
Lymph node metastasis		< 0.001	2.419	1.054-5.552	0.037
Negative	52
Positive	194
Clinical Stage		< 0.001	1.078	0.433-2.685	0.871
I + II	63
III + IV	183
Location		< 0.001	0.762	0.563-1.032	0.079
Upper	108
Middle/lower	138
pathologic differentiation		0.029	0.983	0.688-1.406	0.925
Well + Moderate differentiation adenocarcinoma	71
Poor differentiation adenocarcinoma	175

CI, confidence interval.

^a p value < 0.05.