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. 2014 Jan 15;7(2):751–759.

Table 2.

Associations between the expressions of ANXA1, TREX1 and APE1 and the clinicopathological features

Variables Nuclear ANXA1 Cytoplasmic ANXA1 Nuclear TREX1 Nuclear APE1




Low High P value Low High P value Low High P value Low High P value
Age (years) 0.271 0.334 0.809 0.469
    ≤ 60 18 15 22 11 9 24 10 23
    > 61 40 20 46 14 15 45 14 46
Gender 0.803 1 0.578 0.578
    male 45 26 52 19 17 54 17 54
    female 13 9 16 6 7 15 7 15
Size (cm) 0.83 0.636 0.472 0.811
    > 4 25 14 30 9 12 27 11 28
    ≤ 4 33 21 38 16 12 42 13 41
Pathologic type 0.004 0.376 0.765 0.040
    medullary 19 4 19 4 5 18 8 15
    ulcerative 27 28 40 15 16 39 9 46
    others 11 2 8 5 3 10 6 7
Histologic grade 0.923 0.626 0.349 0.677
    well 9 6 10 5 3 12 3 12
    moderate 39 24 48 15 19 44 18 45
    poor 10 5 10 5 2 13 3 12
LNM 0.263 0.458 0.627 0.617
    positive 25 10 28 7 10 25 7 28
    negative 32 23 39 16 13 42 14 41
AJCC stage 0.764 0.606 0.937
    I 4 3 4 3 3 4 0.293 2 5
    II 32 20 38 14 10 42 12 40
    III 20 9 23 6 10 19 7 22
    IV 1 0 1 0 0 1 0 1