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. 2014 Jan 15;7(2):751–759.

Table 3.

Univariate and multivariable Cox regression analysis of overall survival (n = 93)

Features Univariate analysis Multivariable analysis


HR (95% CI) P value HR (95% CI) P value
Age (years), > 60 vs ≤ 60 1.016 (0.540-1.914) 0.961
Gender, female vs male 0.782 (0.374-1.635) 0.513
Pathologic type, medullary vs others 0.932 (0.564-1.540) 0.784
Histologic grade, 1+2 vs 3 0.648 (0.255-1.649) 0.362
Tumor size (cm), > 4 vs ≤ 4 1.313 (0.703-2.449) 0.393
LNM, positive vs negative 2.181 (1.092-4.357) 0.027 1.425 (0.443-4.591) 0.552
TNM, III+IV vs I+II 2.677 (1.235-5.802) 0.013 3.515 (0.973-12.700) 0.055
Nuclear ANXA1 (low vs high) 0.464 (0.252-0.855) 0.014 0.448 (0.236-0.849) 0.014
Cytoplasm ANXA1 (low vs high) 1.129 (0.554-2.301) 0.738
Nuclear TREX1 (low vs high) 1.138 (0.560-2.316) 0.721
Nuclear APE1 (low vs high) 1.328 (0.635-2.777) 0.451