Table 1.
Clinicopathological variables and p300, CBP and MLL expression
Variables | No. | p300 expression | CBP expression | MLL expression | ||||||
---|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
negative (-) | positive (+) | p value | negative (-) | positive (+) | p value | negative (-) | positive (+) | p value | ||
Age (years) | ||||||||||
< 60 | 162 | 148 | 14 | 0.174 | 74 | 88 | 0.449 | 128 | 34 | 0.522 |
≥ 60 | 60 | 58 | 2 | 24 | 36 | 45 | 15 | |||
Gender | ||||||||||
Male | 140 | 128 | 12 | 0.304 | 65 | 75 | 0.37 | 104 | 36 | 0.087 |
Female | 82 | 78 | 4 | 33 | 49 | 69 | 13 | |||
Smoking history | ||||||||||
No | 103 | 97 | 6 | 0.459 | 44 | 59 | 0.691 | 86 | 17 | 0.063 |
Yes | 119 | 109 | 10 | 54 | 65 | 87 | 32 | |||
ECOG scores | ||||||||||
< 2 | 194 | 180 | 14 | 0.989 | 89 | 105 | 0.171 | 150 | 44 | 0.565 |
≥ 2 | 28 | 26 | 2 | 9 | 19 | 23 | 5 | |||
Lymph node involvement | ||||||||||
No | 111 | 107 | 4 | 0.038 | 49 | 62 | 1 | 90 | 21 | 0.257 |
Yes | 111 | 99 | 12 | 49 | 62 | 83 | 28 | |||
Tumor status | ||||||||||
≥ 3 cm | 139 | 126 | 13 | 0.11 | 61 | 78 | 0.92 | 105 | 34 | 0.267 |
< 3 cm | 83 | 80 | 3 | 37 | 46 | 68 | 15 | |||
p TNM stage | ||||||||||
I + II | 173 | 161 | 12 | 0.769 | 81 | 92 | 0.131 | 133 | 40 | 0.479 |
III + IV | 49 | 45 | 4 | 17 | 32 | 40 | 9 |