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. 2014 Feb 6;15:106. doi: 10.1186/1471-2164-15-106

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Copyright © 2014 Netotea et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Network neighbourhood scores versus sequence similarity. (A) In each comparison X ─ > Y, we only consider the subsets of genes in X with at least one conserved and at least one diverged ortholog-neighbourhood in Y (blue parts of the bars in Figure 6). These genes are divided into genes where the most sequence similar ortholog also has the most conserved neighbourhood (Conserved), the most diverged neighbourhood (Diverged) or neither (Not agreeing). (B) A closer look at the ranks of the most significant ortholog-neighbourhood when sorted by sequence similarity.