. Author manuscript; available in PMC: 2014 Jul 15.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 May 18;86(4):665–670. doi: 10.1016/j.ijrobp.2013.03.035

Table 1. Dose Constraints to Organs at Risk.

Target	Current Dose-Volume Constraints for Standard Fractionated Regimens at our Institution (2-Gy Fractions to 60-74 Gy)	Dose-Volume Constraints in Current Study [BED dose assuming α/β=3 with 15-fraction regimen)
Total Lung	V₂₀ <40% Mean Lung Dose <20 Gy	V₁₇<40% Mean Lung Dose <17.5 Gy(RBE) [17.1 Gy(RBE)]
Liver	40% <50 Gy	40% <40 Gy(RBE) [38.9 Gy(RBE)]
Kidneys (both)	1/3 <20 Gy	1/3 <18 Gy(RBE) [17.1 Gy(RBE)]
Esophagus	20% <70 Gy 50% <50 Gy	20% <55 Gy(RBE) [52.65 Gy(RBE)] 50% <40 Gy(RBE) [38.9 Gy(RBE)]
Heart	50% <30 Gy 40% <40 Gy	50% <25 Gy(RBE) [24.6 Gy(RBE)] 40%<32 Gy(RBE) [31.9 Gy(RBE)]
Spinal Cord	Maximum dose 45 Gy	Maximum dose 36 Gy(RBE) [35.4 Gy(RBE)]
Brachial Plexus	Maximum dose <60 Gy	Dose to <1 cm³ must not exceed 50 Gy(RBE) [45.6 Gy(RBE)]