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Table 2.

Brain antioxidant status in prenatally VitC deficient and control guinea pigs at GD 45 and GD 56.

CTRL GD 45 CTRL GD 56 DEF GD 45 DEF GD 56 Effect of VitC Effect of GD
VitC (nmol/g tissue) 3043±285a 2351±137b 1016±270c 966±242c ⁎⁎⁎ ⁎⁎⁎
α-Tocopherol (nmol/g tissue) 5.5±0.8b 9.0±1.0a 4.6±1.0b 9.4±1.5a NS ⁎⁎⁎
γ-Tocopherol (nmol/g tissue) 0.52±0.46 0.50±0.36 0.80±0.5 0.89±0.39 NS
Superoxide dismutase (U/g tissue) 90±2a 92±2a 133±3b 137±4b ⁎⁎⁎ NS

CTRL: controls; DEF: deficient. GD: gestational day. Values are presented as means±SD. Differences between groups were assessed using two-way ANOVA with diet and GD as factors followed by Tukeys HSD test for individual comparisons. NS: not significant. Different superscript letters indicate that groups are significantly different.

p<0.05.

⁎⁎p<0.001.

⁎⁎⁎p<0.0001.