Table 2.
Brain antioxidant status in prenatally VitC deficient and control guinea pigs at GD 45 and GD 56.
| CTRL GD 45 | CTRL GD 56 | DEF GD 45 | DEF GD 56 | Effect of VitC | Effect of GD | |
|---|---|---|---|---|---|---|
| VitC (nmol/g tissue) | 3043±285a | 2351±137b | 1016±270c | 966±242c | ⁎⁎⁎ | ⁎⁎⁎ |
| α-Tocopherol (nmol/g tissue) | 5.5±0.8b | 9.0±1.0a | 4.6±1.0b | 9.4±1.5a | NS | ⁎⁎⁎ |
| γ-Tocopherol (nmol/g tissue) | 0.52±0.46 | 0.50±0.36 | 0.80±0.5 | 0.89±0.39 | ⁎ | NS |
| Superoxide dismutase (U/g tissue) | 90±2a | 92±2a | 133±3b | 137±4b | ⁎⁎⁎ | NS |
CTRL: controls; DEF: deficient. GD: gestational day. Values are presented as means±SD. Differences between groups were assessed using two-way ANOVA with diet and GD as factors followed by Tukeys HSD test for individual comparisons. NS: not significant. Different superscript letters indicate that groups are significantly different.
⁎p<0.05.
⁎⁎p<0.001.
⁎⁎⁎p<0.0001.