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. Author manuscript; available in PMC: 2014 Feb 17.
Published in final edited form as: Mult Scler Relat Disord. 2012 Oct;1(4):180–187. doi: 10.1016/j.msard.2012.06.002

Table 1.

Trials supporting the use of immunosuppressive drugs in the treatment of NMO.

Drug Date Lead Author Location Population
size
Azathioprine 1998 Mandler United States 7
2008 McKeon United States 10
2010 Bichuetti Brazil 25
2010 Sarhaian Iran 28
2011 Constanzi United States 99
Mycophenolate 2009 Jacob United States 24
Rituximab 2005 Cree United States 8
2008 McKeon United States 8
2008 Jacob United States 25
2011 Bedi United States 23
2011 Pellkofer Germany 10
2011 Kim Korea 30
Methotrexate 2000 Minagar United States 8
Oral corticosteroids 2007 Watanabe Japan 11
Mitoxantrone 2006 Weinstock-
Guttman
United States 5
2011 Kim Korea 20