Density of the phases |
ρ
|
1000 |
kg/m3
|
Diffusion coefficient of oxygen in the interstitial fluid |
|
3.2·10-9
|
m2/sec |
Coefficient δ (eqn (21)) |
δ
|
2.00 |
— |
Intrinsic permeability for interstitial fluid phase |
kls
|
1.8·10-15
|
m2
|
Intrinsic permeability for tumor cell phase |
kts
|
5·10-20
|
m2
|
Adhesion of tumor cells (to ECM) |
at
|
1·106
|
N/m3
|
Growth coefficient of tumor cells (eqn (18)) |
|
0.016 |
— |
Critical mass fraction of oxygen (eqs (18,20)) |
|
3·10-6
|
— |
Critical pressure for cell growth (eqs (18,20)) |
|
1330 |
Pa |
Necrosis coefficient (eqn (19)) |
|
0.016 |
— |
Cells pressure above which necrosis occurs (eqn (19)) |
|
930 |
Pa |
Pressure dependent additional necrosis (eqn (19)) |
|
5·10-4
|
— |
Consumption coefficient related to growth in eqn (20)
|
|
4·10-4
|
— |
Consumption coefficient related to metabolism in eqn (20)
|
|
6·10-4
|
— |
Coefficient σc in eqn (28)
|
σc
|
532 |
Pa |
Coefficient b in eqn (28)
|
b
|
1 |
— |