Table III.
Residual tumour classification and histological examination of the primary tumours for occurrence of apoptosis and tumour regression after PAT-SC1 treatment and gastrectomy.
| R0 patients n=35 n (%) |
R1–R2 patients n=15 n (%) |
ITT population n=51 n (%) |
|
|---|---|---|---|
| Residual tumour classification | |||
| R0 | 35 (68.6) | ||
| R1 | 2 (3.9) | ||
| R2 | 13 (25.5) | ||
| Missing tumour classification | 1 (2.0) | ||
| Apoptosis (consensus) | |||
| Patients evaluated | 34 | 14 | 48 |
| − | 6 (17.6) | 3 (21.4) | 9 (18.8) |
| + | 11 (32.4) | 6 (42.9) | 17 (35.4) |
| ++ | 17 (50.0) | 5 (35.7) | 22 (45.8) |
| Tumour regression (consensus) | |||
| Patients evaluated | 31 | 13 | 44 |
| 0 | 11 (35.5) | 7 (53.8) | 18 (40.9) |
| + | 6 (19.3) | 5 (38.5) | 11 (25.0) |
| ++ | 14 (45.2) | 1 (7.7) | 15 (34.1) |
ITT, intent to treat population.