Table 2.
Top 50 downregulated genes isolated from repetitive hypoxic preconditioning-treated splenic B cells compared to untreated splenic B cells
| Accession | Symbol | Fold change | P value | Abbreviated definition |
|---|---|---|---|---|
|
NM_010389 |
H2-Ob |
−6801.35 |
1.57E-03 |
Histocompatibility 2, O region beta locus (H2-Ob) |
|
NM_010238.1 |
Brd2 |
−65.77 |
1.66E-03 |
Bromodomain containing 2 (Brd2), transcript variant 1 |
|
XM_132218.3 |
2310002F18Rik |
−43.53 |
3.68E-38 |
Coenzyme Q2 homolog, prenyltransferase (yeast) (Coq2), nuclear gene encoding mitochondrial protein |
|
NM_053214.1 |
Myo1f |
−15.52 |
2.26E-03 |
Myosin IF (Myo1f) |
|
AK037780 |
Slam |
−8.51 |
2.00E-03 |
Signaling lymphocyte activation molecule, full insert sequence |
|
NM_008533 |
Ly78 |
−7.47 |
1.60E-03 |
CD180 antigen (Cd180) |
|
XM_284165.2 |
A730013O20Rik |
−6.59 |
1.23E-02 |
Microtubule associated tumor suppressor candidate 2 (Mtus2) |
|
XM_194143.2 |
LOC269542 |
−5.95 |
7.67E-06 |
-This record was discontinued. |
|
NM_026216.1 |
1700096C12Rik |
−5.71 |
1.07E-03 |
Replaced with F-box protein 4 and validated |
|
AK043442 |
Cd38 |
−5.50 |
7.29E-08 |
CD38 antigen, full insert sequence |
|
AK051496 |
D130052N13Rik |
−5.37 |
1.86E-02 |
RIKEN full-length enriched library, clone:D130052N13 product:hypothetical protein, full insert sequence |
|
AK029383 |
4833419P04Rik |
−5.24 |
4.42E-07 |
RIKEN full-length enriched library, clone:4833419P04 product:hypothetical protein, full insert sequence |
|
NM_011579.2 |
Tgtp |
−5.15 |
2.09E-03 |
T cell specific GTPase 1 (Tgtp1) |
|
NM_011926.1 |
Ceacam1 |
−5.09 |
4.97E-02 |
Carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1), transcript variant 3 |
|
AK045295 |
Swap70 |
−5.06 |
1.36E-12 |
SWAP complex protein, 70 kDa, full insert sequence |
|
XM_359052.1 |
LOC386068 |
−4.88 |
2.49E-05 |
-This record was discontinued. |
|
XM_357708.1 |
LOC384553 |
−4.81 |
8.72E-06 |
-This record was discontinued. |
|
AK085749 |
Ceacam1 |
−4.59 |
3.50E-02 |
CEA-related cell adhesion molecule 1, full insert sequence |
|
AK080623 |
A830029A02Rik |
−4.27 |
6.89E-04 |
RIKEN full-length enriched library, clone:A830029A02 product:hypothetical protein, full insert sequence |
|
XM_205896.3 |
LOC277506 |
−4.23 |
2.27E-03 |
-This record was discontinued. |
|
AK038943 |
A230077I10Rik |
−4.18 |
3.45E-02 |
Similar to ENDOGLYCAN, full insert sequence |
|
NM_175128 |
4930430F08Rik |
−4.03 |
1.02E-02 |
RIKEN cDNA 4930430 F08 gene (4930430F08Rik), protein coding |
|
XM_150371.1 |
1700016D02Rik |
−4.01 |
1.45E-02 |
RIKEN cDNA 1700016D02 gene , protein coding |
|
AK040329 |
Tactile-pending |
−3.84 |
3.10E-04 |
T cell activation, increased late expression, full insert sequence |
|
NM_177588.1 |
AW413632 |
−3.82 |
1.26E-02 |
threonine synthase-like 1 (bacterial) (Thnsl1), transcript variant 1 |
|
NM_008493.3 |
Lep |
−3.63 |
6.19E-03 |
Leptin (Lep) |
|
NM_145145.1 |
Pomt1 |
−3.62 |
8.42E-03 |
protein-O-mannosyltransferase 1 (Pomt1) |
|
AK041764 |
Rasgrf2 |
−3.56 |
6.48E-03 |
RAS protein-specific guanine nucleotide-releasing factor 2, full insert sequence |
|
AK011989 |
2610305J24Rik |
−3.49 |
1.38E-03 |
RIKEN full-length enriched library, clone:2610305 J24 product:unclassifiable, full insert sequence |
|
XM_359103.1 |
LOC386168 |
−3.42 |
1.54E-02 |
-This record was discontinued |
|
AK035999 |
9630025O15Rik |
−3.34 |
2.11E-02 |
RIKEN full-length enriched library, clone:9630025O15 product:hypothetical protein, full insert sequence |
|
NM_028595 |
Ms4a6c |
−3.32 |
1.46E-03 |
Membrane-spanning 4-domains, subfamily A, member 6C (Ms4a6c), transcript variant 1 |
|
NM_010797.1 |
Mid1 |
−3.31 |
1.55E-05 |
Midline 1 (Mid1), transcript variant 1 |
|
NM_024291.3 |
Ky |
−3.22 |
9.05E-03 |
Kyphoscoliosis peptidase (Ky) |
|
AK080934 |
Ly116 |
−3.21 |
9.86E-03 |
Membrane-spanning 4-domains, subfamily A, member 4B, full insert sequence |
|
XM_140160.2 |
LOC240168 |
−3.20 |
6.52E-03 |
RAS, guanyl releasing protein 3 (Rasgrp3), transcript variant 2 |
|
AK034620 |
9430015G10Rik |
−3.17 |
1.64E-02 |
RIKEN full-length enriched library, clone:9430015G10, protein coding, validated |
|
AK089281 |
Traf1 |
−3.13 |
4.00E-02 |
Tnf receptor-associated factor 1, full insert sequence |
|
XM_148699.3 |
Crebbp |
−3.08 |
1.25E-12 |
CREB binding protein (Crebbp) |
|
BC016202 |
Dhx30 |
−3.03 |
2.02E-02 |
DEAH (Asp-Glu-Ala-His) box polypeptide 30, mRNA (cDNA clone MGC:27662 IMAGE:4527765), complete cds |
|
AK044748 |
A930039F13Rik |
−2.98 |
2.72E-04 |
Hypothetical RNA-binding region RNP-1 (RNA recognition motif) containing protein, full insert sequence |
|
NM_013730.2 |
Slamf1 |
−2.96 |
4.44E-16 |
Signaling lymphocytic activation molecule family member 1 (Slamf1) |
|
NM_009744.2 |
Bcl6 |
−2.93 |
8.88E-16 |
B cell leukemia/lymphoma 6 (Bcl6) |
|
XM_285750.2 |
LOC332788 |
−2.91 |
3.46E-02 |
-This record was discontinued |
|
NM_177197.2 |
4833405L16Rik |
−2.83 |
3.82E-03 |
Isopentenyl-diphosphate delta isomerase 2 (Idi2) |
|
NM_008739 |
Nsd1 |
−2.80 |
1.67E-13 |
Nuclear receptor-binding SET-domain protein 1 (Nsd1) |
|
NM_001039250.1 |
EG638695 |
−2.79 |
2.82E-02 |
Predicted gene 7247 |
|
NM_011538.1 |
Tbx6 |
−2.76 |
3.57E-03 |
T-box 6 (Tbx6) |
|
XM_358291.1 |
LOC385575 |
−2.76 |
3.08E-08 |
-This record was discontinued |
| XM_132034.1 | Pcdh7 | −2.76 | 3.92E-02 | Protocadherin 7, protein coding, validated |