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Transepithelial transport of chloroquine is several folds lower in P-MDCK cells than MDCK cells. Transport of chloroquine and salicylic acid was assessed using P-MDCK and MDCK cell monolayers grown on transwell filter for 6 days in the presence of 2 mM L-tyrosine. Data are expressed as mean ± SD for n = 6. *P < 0.05 when compared with MDCK cells.
