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The box and whisker plots represent the distribution of numbers of repeated Alu (left panels) and LINE-1 (right panels) elements flanking (+/− 100 Kbp) the indicated sequence classes, i.e. miRNAs (A and A'), UCRs (B and B') and protein-coding genes (C and C'). EFV-downregulated miRNAs (A) and UCRs (B) are highly significantly enriched (**, P≤0.0001) in Alu elements.
