Table 1. Clinicopathological characteristics (N=317).

Variables	HOXA11 hypermethylation		P-value
	No (N=99)	Yes (N=218)
Age*	60 ± 10	60 ± 10	0.73
Pack-years*	32 ± 40	32 ± 27	0.23
Sex
Women	29	53
Men	70	165	0.35
Smoking status
Never	29	66
Former	12	36
current	58	116	0.54
Histology
Adenoca	46	78
Squamous	44	121
Others	9	19	0.17
Differentiation†
Well	21	33
Moderately	40	108
Poorly	13	19
Undifferentiated	2	5	0.24‡
Stage
I	63	124
II	25	53
III	11	37
IV	0	4	0.33‡
Recurrence
No	50	124
Yes	49	94	0.29

Abbreviations: Adenoca, adenocarcinoma; Squamous, squamous cell carcinoma;

^*Values indicate mean ± standard deviation

^†Differentiation data are missing for 76 patients

^‡Based on Fisher's exact test