Figure 3. Gefitinib inhibits EGFR phosphorylation but induces STAT3 activation in lung caner cells.

Cells were subject to time-dependent treatment of gefitinib at 4μM (left panel) and 8μM (right panel) for the indicated time periods. The expression and activity of EGFR, Akt and STAT3 in A549 cells were determined by Western Blot.