Figure 1. (A) PIK3CA mutation status in invasive epithelial tumors of Saudi Breast Cancer patients. The x-axis indicates relative frequency and y-axis shows mutation and change in amino acid. The total 21 missense mutations out of 81 total primary tumor samples (25.9%), 17 in exon 20 (81.0%), and 4 in exon 9 (19.0%). (B) The frequency of C3075T SNP (rs17849079) in disease-free control samples and in breast cancer patient population in Saudi Arabia. The frequency of SNP in breast cancer patients (7/81 or 8.6%) is significantly higher than those with disease-free controls (2/189 or 1.1%). *P value = 0.0032.