Figure 1. The cytotoxic response to PXD101. DB (A and B), OCI-Ly19 (C and D), and SUDHL6 (E and F) cells were treated with PXD101 at the IC₅₀ concentrations determined for each as shown in Table 1. At 0, 24, 48, and 72 h treatment cells were harvested and subjected to Annexin V/PI assay (A, C, and E) or cell cycle analysis (B, D, and F). The graphs shown represent the results of 3–4 independent experiments. Error bars represent SEM.