Table 1.
Variables | Negative biopsy (n=899) | Positive biopsy (n=221) | p value | OR (95% CI) |
---|---|---|---|---|
Age (years) | 64.1 ± 7.5 | 67.1 ± 8.0 | <0.001 | 1.054 (1.033–1.075) |
Volume | 50 (31) | 40 (24) | <0.001 | 0.981 (0.974–0.988) |
Volume quartiles | ||||
12–34 (cc) | 180 (20.1%) | 88 (39.8%) | <0.001 | 3.352 (2.166–5.188) |
35–47 (cc) | 237 (26.4%) | 60 (27.1%) | 0.017 | 1.736 (1.103–2.733) |
48–66 (cc) | 240 (26.8%) | 38 (17.2%) | 0.744 | 1.086 (0.663–1.777) |
67–253 (cc) | 240 (26.8%) | 35 (15.8%) | — | 1.000 |
Total PSA (ng/mL) | 6.9 (3.88) | 8.6 (6.06) | 0.002 | 1.041 (1.015–1.067) |
Free PSA (ng/mL) | 1.2 (0.83) | 1.0 (0.86) | 0.800 | 0.984 (0.869–1.114) |
Free/total PSA (ng/mL) | 0.18 (0.11) | 0.15 (0.10) | <0.001 | 0.021 (0.003–0.180) |
PSA density | 0.13 (0.10) | 0.21 (0.20) | <0.001 | 19.628 (7.123–54.091) |
No. cores | 11.8 ± 4.0 | 13.1 ± 4.6 | <0.001 | 1.072 (1.036–1.108) |
OR: odds ratio; CI: confidence interval; PSA: prostate–specific antigen.