Table 1.

Comparison of clinical characteristics of patients according to biopsy outcome

Variables	Negative biopsy (n=899)	Positive biopsy (n=221)	p value	OR (95% CI)
Age (years)	64.1 ± 7.5	67.1 ± 8.0	<0.001	1.054 (1.033–1.075)
Volume	50 (31)	40 (24)	<0.001	0.981 (0.974–0.988)
Volume quartiles
12–34 (cc)	180 (20.1%)	88 (39.8%)	<0.001	3.352 (2.166–5.188)
35–47 (cc)	237 (26.4%)	60 (27.1%)	0.017	1.736 (1.103–2.733)
48–66 (cc)	240 (26.8%)	38 (17.2%)	0.744	1.086 (0.663–1.777)
67–253 (cc)	240 (26.8%)	35 (15.8%)	—	1.000
Total PSA (ng/mL)	6.9 (3.88)	8.6 (6.06)	0.002	1.041 (1.015–1.067)
Free PSA (ng/mL)	1.2 (0.83)	1.0 (0.86)	0.800	0.984 (0.869–1.114)
Free/total PSA (ng/mL)	0.18 (0.11)	0.15 (0.10)	<0.001	0.021 (0.003–0.180)
PSA density	0.13 (0.10)	0.21 (0.20)	<0.001	19.628 (7.123–54.091)
No. cores	11.8 ± 4.0	13.1 ± 4.6	<0.001	1.072 (1.036–1.108)

OR: odds ratio; CI: confidence interval; PSA: prostate–specific antigen.