Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 17;204(4):541–557. doi: 10.1083/jcb.201307050

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Nazarko et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 9. — ATG37/ACBD5 is essential for pexophagy in human cells. (A and C) ACBD5 is needed for the delivery of peroxisomes to the lysosomes in HeLa (A) and Ntera-2 (C) cells expressing peroxisomally targeted mRFP-EGFP-SKL. Arrows point to the autolysosomes with acid-resistant mRFP fluorescence. Bars, 10 µm. (B) Quantitation of data in A. The percentage of cells with mRFP-labeled autolysosomes is shown as the mean + SD (error bars; n ≥ 50; *, P < 0.05 vs. control siRNA). (D) Quantitation of data in C. The ratio of mRFP and EGFP intensities per cell reflects the occurrence of pexophagy and is presented as the mean + SD (error bars; n ≥ 10 images; *, P < 0.05 vs. control siRNA).