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. 2013 Dec 28;88(3):701–723. doi: 10.1007/s00204-013-1156-8

Table 5.

Proportion of Cat 2 chemicals that were classified according to specific classification drivers

Effects Severity % (n)
1 ≤ COMaj a < 3 CRMaj/CCMaj b ≥ 2 (and COMaj a < 1) 1 ≤ IRMaj a ≤ 1.5 only
RCD (n = 47) 74.5 (35) 25.5 (12) 0.0 (0)
 CRMaj + CCMaj 36.2 (17) 6.4 (3) NA
 CRMaj only 21.3 (10) 17.0 (8) NA
 CCMaj only 6.4 (3) 2.1 (1) NA
 COMaj only 10.6 (5) NA NA
NCD (n = 194) 54.1 (105) 43.3 (84) 2.6 (5)
 CRMaj + CCMaj 14.9 (29) 7.2 (14) NA
 CRMaj only 18.6 (36) 34.0 (66) NA
 CCMaj only 0.5 (1) 2.1 (4) NA
 COMaj only 20.1 (39) NA NA

CO corneal opacity, IR iritis, CR conjunctiva redness, CC conjunctiva chemosis, RCD Reference Chemicals Databases, NCD European New Chemicals Database, NA not applicable

asecond (n = 3 or 4) or third (n = 5 or 6) highest mean score

bThe largest of the second (n = 3 or 4) or third (n = 5 or 6) highest mean CR and CC scores