Figure 1.
Changes in mitochondrial membrane potential following treatment with levetiracetam. (A) Mean fluorescence intensity (MFI) of Mitotracker Red as a measure of relative mitochondrial membrane potential in C17.2 cells at 48 h post treatment with NGF with or without levetiracetam (Lev). (B) MFI Mitotracker Red in C57BL/6 splenocytes 48 h after treatment with or without 0.15 mM Lev. (C) MFI Mitotracker Red in in IiDef splenocytes 48 h after treatment with or without 0.15 mM Lev. (D) Table depicting percent change from NGF treatment alone, compared to NGF treatment in the presence of doses of levetiracetam. *Denotes a p-value < 0.05.