TABLE 1.

Hepatic RE concentrations for 3-month-old male WT, Lrat^−/−, Lrat^−/−/Dgat1^−/−, CrbpI^−/−, and Lrat^−/−/CrbpI^−/− mixed C57Bl/6J/129sv genetic background mice

Strain	n	Hepatic RE (nmole/g tissue)
WT	5	4272.0 ± 828.0
Lrat−/−	4	0.1 ± 0.1ab
Lrat−/−/Dgat−/−	4	0.1 ± 0.1ab
CrbpI−/−	5	679.5 ± 265.8ac
Lrat−/−/CrbpI−/−	5	5.0 ± 3.1a

Mice were maintained for 4 weeks on a diet providing 25 times more retinol than a standard vitamin A-sufficient basal diet. Prior to being placed on the excess-retinol diet, all mice were maintained from weaning on a standard vitamin A-sufficient chow diet. All values are given as mean ± SD.

^aP < 0.01 different from WT mice.

^bP < 0.05 different from CrbpI^−/− mice.

^cP < 0.05 different from Lrat^−/− mice.