TABLE 7.
Intestinal protein levels assessed by LC-MS/MS in the insulin-sensitive and the insulin-resistant subjects
| Proteins | Insulin-Sensitive subjects(n = 10)a | Insulin-Resistant subjects(n = 14)a | %Δ | P |
| ApoB-48 | 0.16 (0.10–0.23) | 0.15 (0.07–0.23) | −6.3 | 0.79 |
| MTP | 1.69 (1.00–2.81) | 1.26 (069–1.73) | −25.4 | 0.05 |
| FABP-2 | 2.27 (1.63–3.32) | 1.73 (0.47–2.7) | −23.8 | 0.05 |
| FATP-4 | 0.09 (0.06–0.13) | 0.07 (0.05–1.00) | −22.2 | 0.04 |
The results are expressed as the molar ratio of the target protein normalized with the enterocyte-specific marker villin (range).
a
Target protein/villin ratio.
b
%Δ represents the percent difference between the two groups.