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. 2014 Feb 15;8:18. doi: 10.1186/1752-0509-8-18

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Copyright © 2014 Hellweger et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Numerical competition experiments. (A) Example of one simulation at intermediate heat shock severity and frequency (H_a = 0.7, F_h = 0.14 d^-1). Cell density of 10 competitors. Abrupt drops in concentrations correspond to heat shocks. (B) Summary of tournament-style competitions. Optimal Tsl1/Tps3 expression parameters for a number of (B1) heat shock severities (H_a varies, F_h = 0.14 d^-1) and (B2) frequencies (H_a = 0.7, F_h varies). Constant: e_c,Tsl1 in μM, Age-dependent: e_a,Tsl1 in μM, Stochastic: f_r,Tsl1 / 10. Symbols are mean +/- one standard deviation of ten replicate experiments.