Skip to main content
. 2011 Jul 13;2(3):449–501. doi: 10.3390/genes2030449

Figure 1.

Figure 1

Figure 1

Figure 1

Correction of the sequence of complement component C7 of Gallus gallus with the FixPred protocol. The DA of GNOMON-predicted sequence of complement component C7 from Gallus gallus (XP_424774) was found to differ from those of its mammalian and fish orthologs (CO7_HUMAN, CO7_PIG, B5X0R1_SALSA): whereas the latter contain TSP_1, Ldl_recept_a, MACPF, TSP_1, Sushi and Sushi domains the ortholog of Gallus gallus lacks the domains downstream of the MACPF domain. The sequence “XP_424774_CORRECTED” was predicted by the use of alternative gene models and is supported by ESTs. The sequence predicted by FixPred was experimentally verified by cloning the full-length cDNA; the cDNA sequence was deposited in GenBank (accession cDNA: HQ878377; accession protein: ADY17228). (a) Comparison of the DAs of XP_424774 and XP_424774_CORRECTED with that of CO7_HUMAN; (b) Alignment of the sequences of XP_424774 and XP_424774_CORRECTED with those P_416936, XP_416936_CORRECTED with those of CO7_HUMAN, CO7_PIG and B5X0R1_SALSA.