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. 2011 Aug 2;2(3):516–561. doi: 10.3390/genes2030516

Figure 2.

Figure 2

Types of homology of multidomain proteins: pseudoparalogs and epaktologs. (a) Pseudoparalogous multidomain proteins with identical DA—cytoplasmic and mitochondrial Leucyl-tRNA synthetase; (b) Pseudoparalogous multidomain proteins with different DA—cytoplasmic Leucyl-tRNA synthetase and mitochondrial Isoleucyl-tRNA synthetase; and (c) Epaktologous proteins sharing homologous domains—human neurotrypsin, human scavenger receptor cysteine-rich domain-containing group B protein, human lysyl oxidase homolog 2 and porcine deleted in malignant brain tumors 1 protein.