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The TE vs. ICM cell fate decision in the mouse embryo. This cell fate decision takes place during the transition from morula (E2.5) to early blastocyst (E3.5). Here regulation of lineage specific transcription factors such as Cdx2, Tead4, Nanog, Oct4 and Sox2, will result in segregation of the first cell lineage trophectoderm (TE) from inner cell mass (ICM).
