Table 3.
Weights of fetuses, placentas and some internal organs of fetuses from dams treated with Tityus bahiensis venom (2.5 mg/kg) on the 5th (GD5) or 10th (GD10) gestational day
| Weight | Control | n | GD5 | n | GD10 | n | p values |
|---|---|---|---|---|---|---|---|
| Fetal weight (g) |
5.10 ± 0.07 |
133 |
5.70 ± 0.04* |
115 |
5.44 ± 0.04* |
129 |
< 0.0001 |
| Absolute placental weight (g) |
0.49 ± 0.01 |
133 |
0.54 ± 0.01* |
115 |
0.53 ± 0.01* |
129 |
0.0010 |
| Relative placental weight (%) |
9.31 ± 0.29 |
133 |
9.96 ± 0.21 |
115 |
9.63 ± 0.14 |
129 |
0.6443 |
| Absolute liver weight (g) |
0.47 ± 0.01 |
66 |
0.49 ± 0.01 |
58 |
0.58 ± 0.01* |
65 |
< 0.0001 |
| Relative liver weight (%) |
8.63 ± 2.06 |
66 |
8.78 ± 1.87 |
58 |
10.49 ± 1.34* |
65 |
< 0.0001 |
| Absolute lung weight (g) |
0.14 ± 0.002 |
66 |
0.15 ± 0.003* |
58 |
0.15 ± 0.002* |
65 |
0.0107 |
| Relative lung weight (%) |
2.59 ± 0.05 |
66 |
2.76 ± 0.05* |
58 |
2.79 ± 0.04* |
65 |
0.0510 |
| Absolute heart weight (g) |
0.04 ± 0.001 |
66 |
0.06 ± 0.001* |
58 |
0.05 ± 0.001* |
65 |
< 0.0001 |
| Relative heart weight (%) |
0.83 ± 0.16 |
66 |
1.06 ± 0.16* |
58 |
0.93 ± 0.14* |
65 |
< 0.0001 |
| Absolute kidney weight (g)≠ |
0.04 ± 0.001 |
66 |
0.04 ± 0.001 |
58 |
0.04 ± 0.001 |
65 |
0.5047 |
| Relative kidney weight (%) |
0.69 ± 0.02 |
66 |
0.67 ± 0.02 |
58 |
0.74 ± 0.02 |
65 |
0.0746 |
| Crown-rump length (cm) | 3.33 ± 0.02 | 66 | 3.47 ± 0.02* | 46 | 3.35 ± 0.02 | 53 | 0.0002 |
Data are expressed as the mean ± SEM. *Significantly different from control; p < 0.05, ANOVA followed by Tukey Kramer. n = number of fetuses. ≠Kidneys were weighed in pairs.