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Inhibition of release of pro-inflammatory cytokines by nCUR versus sCUR. Effect of nCUR and sCUR on secretion of GM-CSF, IL-6, IL-8, MCP-1, VEGF, and TNFα by Detroit cells preincubated for 0 or 60 minutes with 200 μM nCUR (green) or 200 μM sCUR (red) and subsequently infected for 4 hours with live M. catarrhalis strain 25238 (MOI 100). □ (black) indicates the positive control (0 μM CUR, MOI 100). At no time point there is a statistically significant difference between nCUR and sCUR.
