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Cytochrome p450 homologues corresponding to TCE metabolizing enzymes identified by Lash et al., 2000. No CYP2E1 or CYP2B6 homologs have been identified in the chick. CYP2C18 was identified in the human heart its avian homolog is CYP2H1
| P450 | Human | Murine | Chick (% DNA Identity) |
|---|---|---|---|
| Major | CYP2E1 | CYP2E1 | - |
| Minor | CYP1A1 | CYP1A1 | CYP1A4 (66.9) |
| Minor | CYP2C9 | CYP2C | CYP2C45 (61.4) |
| Minor | CYP2B6 | CYP2B2 | - |
|
| |||
| Cardiac | CYP2C18 | CYP2C80 | CYP2H1 (63.4) |
