Table 1.

Odds ratio (OR) and 95% confidence intervals (CI) for prevalence of subclinical hyperthyroidism: effects of age at examination by gender.

Gender Age at examination		Case (76)	Noncase (11,777)	Rate per 103	ORa	95% CI	Test for
							heterogeneityb	trendc
All:	12–14	3	1,243	2.41	0.43	0.10,1.28	0.07	0.05
	15–19	18	3,493	5.13	1
	20–24	30	3,612	8.24	1.61	0.89,2.99
	25–32	25	3,429	7.24	1.37	0.73,2.63
Male:	12–14	1	624	1.60	0.39	0.02,2.20	0.73	0.80
	15–19	8	1,758	4.53	1
	20–24	6	1,879	3.18	0.67	0.22,1.96
	25–32	8	1,802	4.42	0.90	0.32,2.51
	Total	23	6,063	3.78
Female:	12–14	2	619	3.22	0.48	0.07,1.84	0.02	0.03
	15–19	10	1,735	5.73	1
	20–24	24	1,733	13.66	2.42	1.17,5.39
	25–32	17	1,627	10.34	1.76	0.79,4.13
	Total	53	5,714	9.19
Test for interactiond							0.33

^aAll analyses performed with adjustment for gender, place of residency, period of examination, ATPO level, thyroid volume, ultrasound-detected nodules and I-131 dose with the 3-category non-parametric response.

^bBased on the LRT for categorical age effects vs no age effect (df=3).

^cBased on the LRT for logit-linear age effects vs no age effect (df=1).

^dBased on the LRT for the interaction between gender and categorical age effects (df=3).