Table 1.
Characteristics | Metabolically healthy obese subjects (n = 75) | Nonobese controls (n = 80) | P value |
---|---|---|---|
Men/women (n) | 37/38 | 40/40 | 0.93 |
Age (years) | 48.8 ± 11.6 | 47.50 ± 12 | 0.48 |
BMI (kg/m²) | 34.9 ± 3 | 22.7 ± 1.8 | <0.001* |
WC (cm) | 104.6 ± 10.5 | 77.3 ± 6.8 | <0.001* |
SBP (mmHg) | 120.9 ± 9.5 | 116.9 ± 9.8 | 0.01* |
DBP (mmHg) | 75.4 ± 10.5 | 74.3 ± 7.2 | 0.44 |
Fasting glucose (mg/dL) | 88 ± 9.2 | 86.2 ± 8.2 | 0.18 |
Fasting insulin (μIU/mlL) | 9.3 ± 2.7 | 7.2 ± 2.5 | <0.001* |
HOMA-IR | 1.9 ± 0.6 | 1.5 ± 0.6 | <0.001* |
Total cholesterol (mg/dL) | 172 ± 33.1 | 167.9 ± 24.3 | 0.37 |
Triglycerides (mg/dL) | 118.6 ± 23.7 | 111.9 ± 25.9 | 0.001* |
HDL-C (mg/dL) | 53.2 ± 7.3 | 58.6 ± 6.5 | <0.001* |
LDL-C (mg/dL) | 96 ± 25.6 | 86.6 ± 24 | 0.02* |
hs-CRP (mg/L) | 1.6 ± 0.6 | 0.8 ± 0.3 | <0.001* |
IGF-1 (ng/mL) | 203.7 ± 40.3 | 229.4 ± 57.5 | 0.002* |
Carotid IMT (mm) | 0.78 ± 0.15 | 0.67 ± 0.1 | <0.001* |
BMI: body mass index, WC: waist circumference, SBP: systolic blood pressure, DBP: diastolic blood pressure, HOMA-IR: homeostasis model assessment of insulin resistance, HDL-C: high density lipoprotein cholesterol, LDL-C: low density lipoprotein cholesterol, hs-CRP: high sensitivity C-reactive protein, IGF-1: insulin-like growth factor-1, and Carotid IMT: carotid intima media thickness. To converte lipid concentration from mg/dl into mmol/L; for total, HDL, and LDL cholesterol divide mg/dL by 38.6 and for triglycerides divide mg/dL by 88.57. Data are expressed as mean ± standard deviation; *P is significant if <0.05.