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Histological analysis of ankle joints.
| Histological finding | Vehicle-treated controls | FTS | P-value |
|---|---|---|---|
| Synovial proliferation | 1·6 | 1 | 0·03 |
| Fibrin deposition | 0·6 | 0 | 0·03 |
| Acute inflammation | 0·6 | 0 | 0·03 |
| Chronic inflammation | 1·2 | 0·25 | 0·009 |
| Angiogenesis | 0·6 | 0 | 0·03 |
| Tissue oedema | 0·6 | 0 | 0·03 |
| Pannus formation | 1 | 0 | 0·04 |
| Cartilage loss | 0·8 | 0 | 0·004 |
| Bursitis | 1 | 0 | 0·04 |
| Extra-articular infiltrate | 0·8 | 0 | 0·05 |
Average score (0–2); n = 10; Student's t-test. FTS: farnesylthiosalicylic acid.
