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. 2013 Dec 20;5(2):133–137. doi: 10.1021/ml400370w

Table 2. IC50 Values of Maraviroc Derivatives in Neutralization Assays against Indicated Strains.

  IC50 (nM) of Maraviroc derivativesa
HIV-1 strain 1 7 12
92RW (clade A) 1.3 ± 0.5b 8.1a 3.0a
JR-FL (clade B) 1.6 ± 0.3c 7.7 ± 0.5b 5.6 ± 2.0d
YU-2 (clade B) 0.43 ± 0.1b 2.8a 2.5a
MGC26 (clade C) 0.37 ± 0.01b 2.7a 0.8a
a

Average (N = 2).

b

Mean ± SE (N = 3).

c

Mean ± SE (N = 12),

d

Mean ± SE (N = 5).